Nanomedicine startup targets genetic solution to diseases

Published on Wednesday, February 24, 2016

Precision Nanosytems

Vancouver Sun article on UBC venture Precision NanoSystems Inc.

Vancouver-based biotech firm Precision NanoSystems Inc. (PNI) has created a tabletop device that produces “self-assembling” molecules that carry drugs and gene therapies directly into the cells of the human body.

Using the unique physics of fluids at the nano-scale, the NanoAssemblr combines active ingredients — such as therapeutic strands of DNA or RNA — with complementary particles such as fatty molecules to form a kind of armoured transport. The active ingredients are encapsulated until they reach their target.

Nanomedicines were originally developed to deliver toxic molecules directly to the site of disease, such as a tumour, but not anywhere else in the body, said Pieter Cullis, director of the NanoMedicines Research Group at the University of B.C.

“That way, the drug doesn’t make you throw up or lose your hair,” he said.

But the technology has exciting applications in genetic medicine, protecting and delivering swatches of genetic material with great precision, even to a particular location within particular cell types.

Read the full article here.